Progeria Research Foundation - PRF

פרופילי מימון

פתוח לחברי סגל הטכניון בלבד. אנא התחבר\י כדי לצפות בפרופילי המימון של הקרן (בפינה הימנית העליונה).


the mission of the progeria research foundation: 
to discover the cure and effective treatment for progeria and its aging related disorders.

about progeria :

Hutchinson-Gilford Progeria Syndrome ("Progeria", or "HGPS") is a rare, fatal genetic condition characterized by an appearance of accelerated aging in children. Its name is derived from the Greek and means "prematurely old." While there are different forms of Progeria*, the classic type is Hutchinson-Gilford Progeria Syndrome, which was named after the doctors who first described it in England; in 1886 by Dr. Jonathan Hutchinson and in 1897 by Dr. Hastings Gilford.

HGPS is caused by a mutation in the gene called LMNA (pronounced, lamin - a). The LMNA gene produces the Lamin A protein, which is the structural scaffolding that holds the nucleus of a cell together. Researchers now believe that the defective Lamin A protein makes the nucleus unstable. That cellular instability appears to lead to the process of premature aging in Progeria.

Although they are born looking healthy, children with Progeria begin to display many characteristics of accelerated aging at around 18-24 months of age. Progeria signs include growth failure, loss of body fat and hair, aged-looking skin, stiffness of joints, hip dislocation, generalized atherosclerosis, cardiovascular (heart) disease and stroke. The children have a remarkably similar appearance, despite differing ethnic background. Children with Progeria die of atherosclerosis (heart disease) at an average age of thirteen years (with a range of about 8 - 21 years).


פרטי קשר:

ddress:
P.O. Box 3453
Peabody, MA 01961-3453

For Fed Ex or other deliveries ONLY:
2 Bourbon Street 
Suite 208 
Peabody, MA 01960

Phone Number: 
(978) 535-2594

Fax: 
(978) 535-5849

E-mail 
info@progeriaresearch.org


הקרן אינה קרן תחרותית.
אתר הבית: http://www.progeriaresearch.org/index.html