Patient-Centered Outcomes Research Institute – Various Opportunities - Letters of Intent

* Clinical Management of Hepatitis C Infection: seeks to fund pragmatic clinical trials (PCTs), or large-scale observational studies that compare two or more alternatives for addressing prevention, diagnosis, treatment, or management of hepatitis C infection; PCORI is interested in comparative studies that evaluate alternative strategies for planning, implementing and managing care for hepatitis C. The research is expected to examine treatment options as well as systems-level interventions or those aimed at eliminate health or healthcare disparities. $20-million over 5 years.

http://www.pcori.org/announcement/clinical-management-hepatitis-c-infection

* Improving Methods for Conducting Patient-Centered Outcomes Research – Spring 2015 Cycle:

seeking projects to address gaps in methodological research relevant to conducting patient-centered outcomes research (PCOR). Results of these projects will inform future iterations of PCORI’s Methodology Report. The improvement of existing methods will benefit all stakeholders, including researchers planning investigations, policy makers weighing the value of healthcare interventions, and patients, clinicians, and caregivers facing healthcare decisions. $750,000/3 yrs.

http://www.pcori.org/announcement/improving-methods-conducting-patient-centered-outcomes-research-spring-2015-cycle

* Addressing Disparities – Spring 2015 Cycle: seeking to fund comparative effectiveness research (CER) studies that evaluate and compare new and/or enhanced interventions to reduce or eliminate disparities in health and healthcare. Studies in the Addressing Disparities program should focus on overcoming barriers that may disproportionately affect the outcomes of specific groups of patients, or identify best practices for sharing results and information about patient-centered outcomes research across patient groups. $1.5-million/3 yrs.

http://www.pcori.org/announcement/addressing-disparities-spring-2015-cycle

* Communication and Dissemination Research – Spring 2015 Cycle: seeks to fund projects that address critical knowledge gaps in the communication and dissemination process—both the communication and dissemination of research results to patients, their caregivers, and clinicians, as well as the communication between patients, caregivers, and clinicians—in the service of enabling patients and caregivers to make the best possible decisions in choosing among available options for care and treatment. $1.5-million/3 yrs.

http://www.pcori.org/announcement/communication-and-dissemination-research-spring-2015-cycle

* Assessment of Prevention, Diagnosis, and Treatment Options – Spring 2015 Cycle: seeking applications for comparative effectiveness research designed to provide information that would inform critical decisions that face patients and caregivers, clinicians, policy makers, and healthcare system leaders. These decisions must be consequential and be occurring now in the absence of sound evidence about the comparative effectiveness of alternative approaches. There must be substantial potential that patients/caregivers will benefit from the new knowledge in ways that are important to them. The premise of this research is that the new knowledge will inform critical choices by patients and stakeholders in health care. This knowledge will provide insight about the comparative benefits and harms of the options and provide information about outcomes that are important to patients. $2-million/3 yrs.

http://www.pcori.org/announcement/assessment-prevention-diagnosis-and-treatment-options-spring-2015-cycle

* Improving Healthcare Systems – Spring 2015 Cycle: seeking applications to study the comparative effectiveness of alternate features of healthcare systems (e.g., innovative technologies, incentive structures, service designs) intended to optimize the quality, outcomes, and/or efficiency of care for the patients they serve and that have the most potential for sustained impact and replication within and across healthcare systems. Healthcare systems encompass multiple levels (e.g., national, state and local health environments, organization and/or practice settings, family and social supports, and the individual patient) and include entities organized to deliver, arrange, purchase, and/or coordinate healthcare services. PCORI seeks to fund studies that will provide information of value to patients, their caregivers, clinicians, and healthcare leaders regarding which features of delivery systems lead to better patient-centered outcomes so they may ultimately impact healthcare delivery. $5-million large studies/5 yrs; $1.5-million small studies/3 yrs.

http://www.pcori.org/announcement/improving-healthcare-systems-spring-2015-cycle